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An elderly woman suffered a severe drop in blood pressure and body temperature after being poisoned by trendy fruit juice.
The unnamed patient, 64, suffered sudden weakness, nausea and vomiting just minutes after drinking calabash juice. The trendy drink has risen in popularity in recent years for its purported ability to reduce stress.
The woman was admitted to a local ER diagnosed with ‘toxic squash syndrome’ – a rare but potentially deadly disease that occurs when a person consumes a dangerous amount of cucurbitacin, a naturally occurring toxin in calabash.
Her blood pressure rapidly dropped to a dangerously low level and she could have died if she did not quickly seek medical attention.
The report is revealed as physicians also warn against other popular wellness trends, like taping a person’s mouth shut while sleeping to enhance breathing.
An unnamed woman suffered ‘toxic squash poisoning’ after she drank calabash juice. She noted that the drink was more bitter than usual. Her symptoms came about fast and dropped her blood pressure to dangerously low levels. She would survive after five days in the hospital (file photo)
The story was reported as a case report in the Canadian Journal of Emergency Medicine.
While the woman regularly enjoyed the drink – she noted to doctors that this time it was even more bitter.
This is a sign that there were higher levels of the toxic chemicals – which are found in gourds like pumpkins, cucumbers and calabash.
The toxin interrupts the ability for the body’s cells to send signals to one another – disrupting normal bodily functions and causing potentially deadly complications.
It also weakens cell defenses, making them more vulnerable to infections and other illnesses.
Centuries of plant domestication and food science have allowed humans to grow gourds with inconsequential levels of the toxin.
Improved farming practices by amateur farmers can lead to the plants growing with concentrations of cucurbitacin that are dangerous to humans.
However, improper farming techniques could lead to an overabundance of them in some plants.
It was a homemade drink that the woman had regularly purchased at a local store.
She was also already suffering from high blood pressure and an overactive thyroid – a gland in the neck that distributes hormones around the body.
The woman suffers symptoms immediately after consuming the drink, including diarrhea and abdominal pain.
Her blood pressure dropped to unhealthy levels, from 142/90 to 46/27 in a matter of minutes when doctors examined her.
A level below 90/60 is considered dangerous, putting a person at risk of a stroke or heart attack.
She was also taking 18 breaths per minute, slightly more than the safe threshold of 16 per minute for a resting person, which could be an indication of lung or heart failure.
Her body temperature also fell from around 100 to 96F, lower than what is safe for adults but not low enough to be considered hypothermia. The woman’s extremities were also cold and tender to touch.
Over the next five days, she continued to have her blood pressure drop to unhealthy levels before rebounding later.
She was treated with electrolytes, drugs for high blood pressure and injections that would help diffuse acid in her stomach. The woman’s condition was resolved after five days.
Cucurbitacin is a bitter toxic substance whose purpose is to protect the plant from animals and bugs that may try to eat it.
Its ability to disrupt normal cell functions could prove valuable in the medical field.
It has shown promise in medicine, with the toxin having antitumor and anti-inflammatory properties

photo by: Ariana Figueroa/States Newsroom
US Sen. Amy Klobuchar, D-Minn., and US Sen. Mike Lee, R-Utah, appear at a Nov. 29, 2022, US Senate hearing on the proposed merger of grocery chains Kroger and Albertsons.
Hanukkah in Austin is coming up soon, from Sunday, December 18 through Monday, December 26. There are several Austin restaurants, bars, and organizations partaking in takeout Hanukkah meals, dishes, and even cocktails. Relatedly, Eater explored the city’s best Jewish foods.
Kitty Cohen’s
2211 Webberville Road, East Austin
The patio-friendly bar brought back its multi-week Hanukkah cocktail pop-up again this holiday season. The Get Lit bar features themed cocktails. Co-owner Josh Brownfield, who is Jewish himself, consulted his rabbi brother-in-law for the pop-up. New to this year’s celebrations will be a JewBoy Burgers pop-up on the first night of Hanukkah (Sunday, December 18) and Hanukkah cookies and rugelach by pastry chef Amanda Rockman Partial proceeds will go towards Shalom Austin.
Dates: Friday, December 1 through Friday, December 30
Midnight in the Garden
To be disclosed after buying tickets
Austin chefs Amanda Rockman and Laura Sawicki are joining forces to host two Hanukkah dinners with the lauded pop-up with a multi-course meal. It’s $200 per person, and the meals take place.
Dates: Saturday and Sunday, December 10 and 11 at 6:45 pm
Temple Beth Shalom
7300 Hart Lane, South Austin
Members and guests of the Austin synagogue can go to its Hanukkah party, with lots of holiday food like latkes and sufganiyot from the catering company Royal Fig Catering, music and activities.
Dates: Sunday, December 18, 5 to 8 p.m
Shalom Austin
Kitty Cohen’s, 2211 Webberville Road, East Austin
The Jewish community organization is taking advantage of Kitty Cohen’s Hanukkah pop-up (see above) by hosting a party through its young adult division group 3Sixty Club. Tickets for the Mazel Ball are $10 in advance, $15 at the door, and free for members.
Dates: Saturday, December 24, 9 to 11 p.m
Know of any Hanukkah events or specials? Let Eater know through [email protected]